N-(trans-4-Morpholinocyclohexyl)-5-(tetrahydro-2H-pyran-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
AZ1495
CAS: 2196204-23-4
Molecular Formula: C21H31N5O2
N-(trans-4-Morpholinocyclohexyl)-5-(tetrahydro-2H-pyran-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine - Names and Identifiers
N-(trans-4-Morpholinocyclohexyl)-5-(tetrahydro-2H-pyran-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine - Physico-chemical Properties
| Molecular Formula | C21H31N5O2 |
| Molar Mass | 385.5 |
| Density | 1.265±0.06 g/cm3(Predicted) |
| pKa | 13.07±0.50(Predicted) |
| Storage Condition | 2-8℃ |
| Use | AZ1495 (compound 28) is an orally active inhibitor of interleukin-1 receptor-associated kinase 4 (IRAK4) with IC50 values of 5 nM and 23 nM for IRAK4 and IRAK1, respectively. With |
N-(trans-4-Morpholinocyclohexyl)-5-(tetrahydro-2H-pyran-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine - Introduction
AZ1495 is an organic compound with the chemical formula C6H9N5O3, usually in the form of a powder. The following is a description of the nature, use, preparation and safety information of AZ1495:
Nature:
-Appearance: AZ1495 is a white to light yellow crystalline powder.
-Solubility: It has good solubility in water and can be dissolved in organic solvents.
-Stability: AZ1495 is stable under regular storage conditions.
Use:
-Catalyst: AZ1495 is often used as a ligand for metal catalysts and is used in organic synthesis reactions.
-Pharmaceutical field: It is also used in synthetic drugs and pharmaceutical research, with anti-viral, anti-cancer and other potential applications.
Preparation Method:
The preparation method of AZ1495 can be realized by the method of synthetic chemistry, in which the specific steps and reaction conditions depend on the specific research needs and synthesis route.
Safety Information:
AZ1495 has low toxicity under general operating conditions, but as an organic compound, it still needs to pay attention to safe operation:
-Avoid direct contact with skin and eyes, wear appropriate protective gloves and glasses.
-Avoid inhaling dust during operation and ensure that the operating area is well ventilated.
-Store in a dry, well-ventilated place, away from heat and fire.
Nature:
-Appearance: AZ1495 is a white to light yellow crystalline powder.
-Solubility: It has good solubility in water and can be dissolved in organic solvents.
-Stability: AZ1495 is stable under regular storage conditions.
Use:
-Catalyst: AZ1495 is often used as a ligand for metal catalysts and is used in organic synthesis reactions.
-Pharmaceutical field: It is also used in synthetic drugs and pharmaceutical research, with anti-viral, anti-cancer and other potential applications.
Preparation Method:
The preparation method of AZ1495 can be realized by the method of synthetic chemistry, in which the specific steps and reaction conditions depend on the specific research needs and synthesis route.
Safety Information:
AZ1495 has low toxicity under general operating conditions, but as an organic compound, it still needs to pay attention to safe operation:
-Avoid direct contact with skin and eyes, wear appropriate protective gloves and glasses.
-Avoid inhaling dust during operation and ensure that the operating area is well ventilated.
-Store in a dry, well-ventilated place, away from heat and fire.
Last Update：2024-04-09 19:05:03
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